Results
PMID | 15749523 |
Gene Name | EGFR |
Condition | Endometriosis |
Association |
Associated |
Mutation | EGFR ( 2073*T) |
Sex | Female |
Associated genes | EGFR |
Other associated phenotypes |
Endometriosis, leiomyomas |
Fertil Steril. 2005 Mar;83(3):796-9. Hsieh, Yao-Yuan| Chang, Chi-Chen| Tsai, Fuu-Jen| Lin, Cheng-Chieh| Tsai, Chang-Hai Department of Obstetrics and Gynecology, China Medical University Hospital, Taichung, Taiwan. Epidermal growth factor receptor (EGFR) is a regulator of angiogenesis and mediator of sex steroid-induced cell growth and differentiation. We observed that EGFR gene 2073*T-related genotypes and allele are associated with higher susceptibilities to endometriosis and leiomyoma. Mesh Terms: Endometriosis/*genetics| Female| Gene Frequency| Genetic Predisposition to Disease| Genotype| Heterozygote| Homozygote| Humans| Leiomyoma/*genetics| *Polymorphism, Genetic| Receptor, Epidermal Growth Factor/*genetics| Uterine Neoplasms/*genetic |